The effects of the 3-day, 4-hour ketamine treatment on the appearance of the face can be subtle.

Three weeks after the ketamine coma procedure the research subject suffered an acute exacerbation of CRPS associated with swelling in the face. Following a 3-day, 4-hour ketamine treatment swelling and allodynia of the face decreased. (Upper photo with transition)

The lower panel of photos are marked equal distant from the medial angle of the eyes. These marks illustrate that the photos of the head are of the same size.